In a large skillet, heat olive oil over medium heat. Add the ground chicken and cook until browned and fully cooked through, about 6-8 minutes. Stir occasionally to break up the meat into smaller pieces.
Lower the heat and pour in the heavy cream, stirring well to combine with the chicken. Allow it to simmer for 2-3 minutes.
Stir in the garlic powder, onion powder, Italian seasoning, salt, and pepper. Mix until everything is well incorporated.
Gradually add the grated Parmesan cheese to the skillet, continuing to stir until the cheese melts and the sauce thickens, about 3-4 minutes. If the mixture is too thick, you can add a splash of chicken broth or water.
While the sauce simmers, toast the whole wheat burger buns in another skillet or toaster until golden brown.
Spoon a generous portion of the creamy chicken Alfredo mixture onto the bottom half of each toasted bun.
Sprinkle chopped fresh parsley over the top for a pop of color and freshness, then top with the other half of the bun.
Notes
For a lighter version, use low-fat cream and cheese.